Endocrine Abstracts

Objective: One of the major problems related to the use of CSII, or intensive insulin regimens in general, is the calculation of accurate insulin boluses. Abolus calculator incorporated into the insulin pump, estimates the dose of insulin to be administered at the meal on the basis of the following parameters: current blood glucose, grams of carbohydrate in the meal, carbohydrate to-insulin ratio (CIR), insulin sensitivity factors (ISF), target blood glucose and quantity of in...

Objective: To evaluate changes in gut microbiota induced by treatment in patients with gestational diabetes mellitus (GDM) treated with insulin in comparison to those treated with metformin.Material and methods: Thirty-one patients with GDM not controlled by diet, included in MeDiGes study (‘Efficacy of metformin in gestational diabetes not controlled by diet in comparison to insulin’), were aleatorized to receive insulin (n=14) or met...

We present the clinical case of a family with an initial diagnosis of AIP syndrome with AIP mutation and a secondary diagnosis of MEN syndrome associated because of a large MEN-1 gen deletion. A male patient 16 years old was evaluated because of delayed growth and pubertal development. He had headaches, nausea and vomits since seven years old. MRI showed: Large pituitary mass of 47.6×22×47.2 mm that erode the floor of the sella, extending into the left prepontine cis...

Adrenal insufficiency is a common complication of transsphenoidal surgery (TSS) for pituitary adenoma. It is very important to identify patients requiring glucocorticoid replacement, minimising risks of adrenal insufficiency.Aim: To assess the performance of early (3° day) post-TSS 08:00 a.m. cortisol measurement to detect and exclude secondary adrenal insufficiency.Methods: We selected patients undergoing TSS in our hospital ...

Introduction: Thyroid ultrasound is a widely used tool in monitoring thyroid nodule, allowing us to assess the size and other sonographic signs suspicious of malignancy, facilitating decisions about diagnosis and treatment.Objectives: To evaluate the presence of ultrasonographic signs suggestive of malignancy in patients with thyroid carcinoma in our hospital.Material and methods: Retrospective study of 63 patients with thyroid car...